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Editorial Pancreatic cancer is the second most common cause of cancer death among all gastrointestinal cancers. It continues to be a devastating disease and only a limited number of patients can be cured. Within the last decade there was truly significant progress in understanding basic cellular and molecular pathways which influence the course of this disease. Therefore, there are reasons to believe that these advances in molecular research represent on of the most likely resource from which significant improvements in the management of pancreatic cancer are to come for the future.

New molecular aspects in pathogenesis and progression of pancreatic cancer