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Background Primary or transmitted HIV-1 drug resistance has caused an alarm in developed countries. While certain HIV-1 subtype C polymorphisms in relation to consensus subtype B sequences are known, there still exists a debate on the validity of these mutations being associated with/mistaken as, primary resistance. In this preliminary study, we have determined polymorphisms in reverse transcriptase (RT) and protease (PR) genes of HIV-1 subtype C from Mumbai, India.

Polymorphisms in reverse transcriptase and protease genes of HIV-1 subtype C from Mumbai