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Abstract Background <it>Helicobacter pylori (H. pylori)</it> has been etiologically linked with primary gastric lymphoma (PGL) and gastric carcinoma (GC). There are a few reports of occurrence of both diseases in the same patient with <it>H. pylori</it> infection. Case presentation We report a patient with PGL in whom the tumor regressed after surgical resection combined with eradication of <it>H. pylori</it> infection. However, he developed GC on follow up; this was temporally associated with recrudescence / re-infection of <it>H. pylori.</it> This is perhaps first report of such occurrence. Conclusions Possible cause and effect relationship between <it>H. pylori</it> infection and both PGL and GC is discussed. This case also documents a unique problem in management of PGL in tropical countries where re-infection with <it>H. pylori</it> is supposed to be high.</p

bmc gastroenterology

Gastric adenocarcinoma in a patient re-infected with H. pylori after regression of MALT lymphoma with successful anti-H. pyloritherapy and gastric resection: a case report