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Background  The surface of polymeric tracheotomy tubes is a favourable environment for biofilm formation and therefore represents a potential risk factor for the development of pneumonia after tracheotomy. The aim of this  in-vitro  study was to develop octenidine-dihydrochloride (OCT) coated polymer tracheotomy tubes and investigate any effects on  Staphylococcus (S.) aureus  and  Pseudomonas (P.) aeruginosa  colonization. Additionally the resistance of the OCT coating was tested using reprocessing procedures like brushing, rinsing and disinfection with glutaraldehyde    Results   Contamination with S. aureus : Before any reprocessing, OCT coated tracheotomy tubes were colonized with 10 3  cfu/ml and uncoated tracheotomy tubes with 10 5  cfu/ml (P = 0.045). After reprocessing, no differences in bacterial concentration between modified and conventional tubes were observed.   Contamination with P. aeruginosa : Before reprocessing, OCT coated tubes were colonized with 10 6  cfu/ml and uncoated tubes with 10 7  cfu/ml (P = 0.006). After reprocessing, no significant differences were observed.    Conclusion  OCT coating initially inhibits  S. aureus  and  P. aeruginosa  colonisation on tracheotomy tubes. This effect, however, vanishes quickly after reprocessing of the tubes due to poor adhesive properties of the antimicrobial compound. Despite the known antimicrobial effect of OCT, its use for antimicrobial coating of tracheotomy tubes is limited unless methods are developed to allow sustained attachment to the tube.

bmc microbiology

The antimicrobial effect of Octenidine-dihydrochloride coated polymer tracheotomy tubes on Staphylococcus aureus and Pseudomonas aeruginosa colonisation