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A reanalysis of the sequences reported by Hoegg  et al  has highlighted the presence of a putative HoxC1a gene in  Astatotilapia burtoni . We discuss the evolutionary history of the HoxC1a gene in the teleost fish lineages and suggest that HoxC1a gene was lost twice independently in the Neoteleosts. This comment points out that combining several gene-finding methods and a Hox-dedicated program can improve the identification of Hox genes.

Comparative phylogenomic analyses of teleost fish Hox gene clusters: lessons from the cichlid fish Astatotilapia burtoni: comment