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Models of the dynamics of interstitial fluid-based continuous glucose sensors imply a variable sensor deviation from reference blood glucose (BG), depending on both sensor calibration procedure and BG dynamics. These effects could have a significant effect on the cross-interpretation of nonidentical accuracy studies.

journal of diabetes science and technology

Modeling of Calibration Effectiveness and Blood-to-Interstitial Glucose Dynamics as Potential Confounders of the Accuracy of Continuous Glucose Sensors during Hyperinsulinemic Clamp