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Hypertriglyceridaemia (HTG), glucose intolerance, insulin resistance and elevated plasma activity of plasminogen activator inhibitor (PAI)-1 are risk factors for ischaemic heart disease. Because these conditions tend to cluster in the same individuals, the concerted action of gemfibrozil on all these parameters were investigated in a patient group with primary HTG.

Effects of Gemfibrozil Therapy on Glucose Tolerance, Insulin Sensitivity and Plasma Plasminogen Activator Inhibitor Activity in Hypertriglyceridaemia