Open AccessLeft ventricular remodelling after acute myocardial infarction: Impact of clinical, echocardiographic parameters and polymorphism of angiotensinogen gene
Author(s) -
Diana Žaliaduonytė-Pekšienė,
Sandrita Šimonytė,
Vaiva Lesauskaitė,
Jolanta Justina Vaškelytė,
Olivija Gustienė,
Vaida Mizarienė,
Renaldas Jurkevičius,
Giedrė Jarienė,
Abdonas Tamošiūnas,
Remigijus Žaliūnas
Publication year - 2013
Publication title -
jraas. journal of the renin-angiotensin-aldosterone system/journal of the renin-angiotensin-aldosterone system
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 46
eISSN - 1752-8976
pISSN - 1470-3203
DOI - 10.1177/1470320312471228
Subject(s) - myocardial infarction , medicine , cardiology , ventricular remodeling , infarction , electrocardiography in myocardial infarction , heart failure , genotype , ejection fraction , biology , gene , biochemistry
The development of left ventricular remodelling after acute myocardial infarction is a predictor of heart failure and mortality. The purpose of the present study was to assess whether the polymorphism of angiotensinogen (AGT) gene with threonine (T) instead of methionine (M) at amino acid 235 in exon 2 (M235T) had effects on cardiac remodelling after acute myocardial infarction.