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Objective   To characterize frailty phenotype in a representative cohort of older Americans and examine determinants of health factors.Methods   Retrospective analysis of data from 5,553 adults ≥60 years old in the 2011–2016 cross-sectional National Health and Nutrition Examination Survey (NHANES). World Health Organization “ Determinants of Health” conceptual model was used to prioritize variables for multinomial logistic regression for the outcome of modified Fried frailty phenotype.Results   482 participants (9%) were frail and 2432 (44%) prefrail. Four factors were highly associated with frailty: difficulty with ≥1 activity of daily living (77%; OR 24.81 p  2 comorbidities (27%; OR 3.33 p &lt; 0.01), and polypharmacy (66%; OR 2.38 p &lt; 0.01).Discussion   A modified Fried frailty assessment incorporating five self-reported criteria may be useful as a rapid nursing screen in low-resource settings. These assessments can streamline nursing care coordination and case management activities, thereby facilitating targeted frailty interventions to support healthy aging in vulnerable populations.

Frailty and Determinants of Health Among Older Adults in the United States 2011–2016