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The introduction, over the past few years, of a large number of orally-active progestagens presents the clinician with serious problems of choice. If all these substances behaved in the same way, and differed merely in potency ratio, the situation would be fairly straightforward, though, as will appear, not entirely simple of solution. But animal experiment, and limited clinical experience, suggests that marked qualitative differences also exist, so that the agent of choice for one indication is likely to prove unsuitable for another. In other words, although some progestagens, by reason oflow potency, will have little to recommend themselves for any indication, other,

Actions and Uses of Orally Active Progestational Steroids