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Coronavirus Infection De Chang1,4* MD&PhD, Guoxin Mo1* MD, Xin Yuan2* MD, Yi Tao1 MD, Xiaohua Peng5 MD, Fusheng Wang2✉ MD, Lixin Xie1✉ MD, Lokesh Sharma5# PhD, Charles S. Dela Cruz5# MD&PhD, Enqiang Qin#2✉ MD 1. College of Pulmonary and Critical Care Medicine, Chinese PLA General Hospital, Beijing 100083, China 2. College of Infectious Disease, Chinese PLA General Hospital, Beijing 100083, China 3. Department of Critical Care Medicine, 5th center of Chinese PLA General Hospital, Beijing 100039, China 4. 3rd Medical Center, Chinese PLA General Hospital, Beijing 100083, China 5. Section of Pulmonary and Critical Care and Sleep Medicine, Department of Medicine, Yale University School of Medicine, New Haven, CT 06520, USA * First authors contributed equally: De Chang, Guoxin Mo and Xin Yuan # Senior authors contributed equally: Lokesh Sharma, Charles S. Dela Cruz and Enqiang Qin ✉ Corresponding authors: Fusheng Wang(fswang302@163.com, Lixin Xie (2464277169@qq.com), Enqiang Qin(qeq2004@sina.com) Total word count: 998 words. Page 1 of 12

Time Kinetics of Viral Clearance and Resolution of Symptoms in Novel Coronavirus Infection