English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Tools annual

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Presents the access of premium content as premium feature

Premium Content

Global: Zendy Plus annual

Global: Zendy Free Plan

P84 Background: Previous studies suggest associations between  pattern of alcohol consumption and blood pressure levels. However,  there is little information on years-long patterns and blood pressure.  Aim: Assess relationship of year-to-year variability in alcohol intake  to blood pressure in alcohol users of the Usual Care (UC) group,  Multiple Risk Factor Intervention Trial. Methods: 6,438 men from the  MRFIT Usual Care group. Data on alcohol variability, blood pressure  (BP) and confounding variables from five 24-hour dietary recalls and BP  measurements at years 0,1,2,3, and 6. The intra-individual coefficient  of variability (CV) in alcohol intake was computed for three  sub-groups, defined by mean of reported intake: sub-group 1, less than  2 drinks/d; sub-group 2, 2-3 drinks/d; sub-group 3, more than 3  drinks/d. Multiple linear regression models --dependent variable blood  pressure --were adjusted for mean alcohol intake, age, ethnicity,  education, BMI, cigarette smoking, serum cholesterol, special diet,  mean calories (in per day models), and mean dietary sodium and  potassium intake. Results: Alcohol variability was inversely and  significantly related to systolic and diastolic blood pressure in the  whole group with alcohol expressed both as grams per day (e.g., for  SBP: β= -0.026488, z=-2.132) and per cent energy (e.g., for SBP: β=  -0.028594, z=-3.371). In sub-group 1 (n=5,128), the association was  inverse but not significant; in sub-group 2 (n=1,073), the association  was inverse and significant; in sub-group 3 (heavy drinkers) (n=237),  the association was direct but not significant. Conclusions: Whereas  year-to-year variability in reported alcohol intake was inversely  related to blood pressure in men reporting less than 3 drinks/d, in  heavy drinkers this evidence of erratic intake was associated with  higher blood pressure.

Alcohol Variability and Blood Pressure: Results from the Usual Care Group of the Multiple Risk Factor Intervention Trial (MRFIT)