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• In recent years interest has been renewed in the role of baroreceptors in hypertension. It was emphasized again by Heymans and Neil that the baroreceptors function not only as regulators, but also as moderators, since they constantly decrease high central sympathetic vasoconstrictor and cardiac accelerator outflow to normal levels. Bemoval of this function by disruption of the buffer nerves results in the well-known experimental neurogenic hypertension. Despite their apparently important function in cardiovascular regulation, it is not clear what role they do play in the pathogenesis of hypertension. Since experimental neurogenic hypertension and human hypertension differ in several ways, any participation of the baroreceptors in the mechanism of either human or experimental non-neurogenic hypertension has been doubted by many investigators.

Mechanism of the Carotid Sinus in Experimental Hypertension