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To the Editor:We read with interest the article by Rodriguez Hernandez et al1 describing a significant difference between left and right common carotid artery intima-media thickness (mean CCA-IMT±SD, 0.75±0.11 mm versus 0.71±0.11 mm; P <0.001) in 102 untreated hypertensive patients. Furthermore, the authors found a significantly higher rate of left-sided nonlacunar ischemic strokes in a population-based stroke registry sample (odds ration [OR]=1.39 for atherosclerotic and OR=1.46 for cardioembolic strokes, respectively; P <0.001).1 They concluded from their findings that potential left side predilection for cerebrovascular events may be eventually related to increased hemodynamic stress and intimal damage as indicated by a significantly increased left CCA-IMT …

Intima-Media Thickness Side Differences Are Limited to the Common Carotid Artery