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Since the endorsement of GeneXpert MTB/RIF by the WHO, many countries have embarked on implementing this technology.  Objective:  We outline the cost of installing GeneXpert in district hospitals in Abuja, Nigeria.    Methods  We prospectively documented costs related to the installation of GeneXpert at five sites. Costs were collected from receipts received from suppliers and normalized to USD 2012 values.    Results  Costs were often identified after initiating installation for many reasons. Installation varied widely between sites with sufficient space and power supply; sites with insufficient space or power supply and costs not directly associated with site installation. The basic cost for installation was USD 2,621.98 per machine. Sites that required additional space cost close to USD 7,000.00.    Conclusion  Space and power requirements have a significant effect on installation costs. Countries need to carefully consider the placement of Xpert machines based on the quality and size of the available infrastructure.

The hidden costs of installing xpert machines in a tuberculosis high-burden country: experiences from Nigeria