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To determine whether treatment with interleukin-1 receptor antagonist (IL1-ra) would affect amniotic fluid concentrations of tumor necrosis factor alpha (TNF-alpha) and prostaglandins or clinical or microbiological outcomes in a model of ascending bacterial infection in pregnancy.

A Randomized Controlled Trial of Interleukin‐1 ReceptorAntagonist in a Rabbit Model of Ascending Infection in Pregnancy