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Another reviewer of this work has questioned "whether hedonism is an appropriate metaphor for brain research" [1, p24]. For Klopf however, hedonism is clearly much more than a metaphor. On the contrary, he sees hedonism as a phenomenon which is exhibited by systems - both social structures and individual organisms - as a direct result of their construction from hedonistic building blocks. The hedonistic neuron is hypothesized as being the most elementary such component of living systems.

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Review of "The Hedonistic Neuron: A Theory of Memory, Learning &amp; Intelligence by A. Harry Klopf", Hemisphere Publishing Corporation, Washington, 1982, ISBN 0-89116-202-X.