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We study the production of a photon pair in association with two bottom jetsat the LHC. This process constitutes an important background to double Higgsproduction with the subsequent decay of the two Higgs bosons into a pair ofphotons and b-quarks respectively. We calculate this process at next-to-leadingorder accuracy in QCD and find that QCD corrections lead to a substantialincrease of the production cross section due to new channels opening up atnext-to-leading order and their inclusion is therefore inevitable for areliable prediction. Furthermore, the approximation of massless b-quarks isscrutinized by calculating the process with both massless and massive b-quarks.We find that the massive bottom quark leads to a substantial reduction of thecross section where the biggest effect is however due to the use of a fourflavor PDF set and the corresponding smaller values for the strong couplingconstant.

Diphoton production in association with two bottom jets