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Direct repeat spoligotyping of 85 paraffin-embedded lung biopsies was used to investigated the occurrence around Beijing of the Beijing family ofMycobacterium tuberculosis . Samples ranged in time from 1956 to 1990. Hybridization patterns were found with 49 (58%) samples, and 45 (92%) produced typical Beijing family patterns extending over the 34-year period.

Retrospective Analysis of the Beijing Family of Mycobacterium tuberculosis in Preserved Lung Tissues