Open Access
“ Mycobacterium ulcerans subsp. shinshuense ” Isolated from a Skin Ulcer Lesion: Identification Based on 16S rRNA Gene Sequencing
Author(s) -
Kazue Nakanaga,
Norihisa Ishii,
Koichi Suzuki,
Kazunari Tanigawa,
Masamichi Goto,
Tsutomu Okabe,
Hajime Imada,
Akemi Kodama,
Tomotada Iwamoto,
Hiroshi Takahashi,
Hajime Saito
Publication year - 2007
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.01041-07
Subject(s) - 16s ribosomal rna , mycobacterium ulcerans , biology , microbiology and biotechnology , ribosomal rna , buruli ulcer , virulence , gene , genetics , medicine , pathology , disease
We describe the fourth reported case involving “Mycobacterium ulcerans subsp.shinshuense .” Compared to previous cases, the infection was more invasive with extensive ulceration from the elbow to the forearm. Definitive identification involved IS2404 detection, 16S rRNA gene sequencing, and analysis of the 16S rRNA gene 3′-terminal region and the virulence plasmid pMUM001.