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A retrospective examination of quantitation standard growth curves associated with 1,000 unique clinical serum specimens tested by a laboratory-developed TaqMan hepatitis C virus analyte-specific reagent-based assay revealed anomalous growth curves associated with 0.40% (95% confidence interval, 0.11% to 1.00%) of these specimens.

journal of clinical microbiology

Anomalous Quantitation Standard Growth Curves in a Laboratory-Developed Hepatitis C Virus (HCV) RNA Quantification Assay Using the TaqMan HCV Analyte-Specific Reagent