Alteration in Bacterial Morphology by Optochin and Quinine Hydrochlorides | Zendy

Arnold S. Kreger | Zendy; D. C. Swartzendruber | Zendy; R H Olsen | Zendy

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Alteration in Bacterial Morphology by Optochin and Quinine Hydrochlorides

Author(s) -

Arnold S. Kreger,

D. C. Swartzendruber,

R H Olsen

Publication year - 1969

Publication title -

journal of bacteriology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.652

H-Index - 246

eISSN - 1067-8832

pISSN - 0021-9193

DOI - 10.1128/jb.97.1.362-366.1969

Subject(s) - quinine , biology , microbiology and biotechnology , bacteria , hydrochloride , incubation , biochemistry , malaria , genetics , immunology

Incubation of washed bacterial and ribosomal suspensions with optochin or quinine hydrochloride caused an increase in the turbidity of the suspensions and the appearance of electron-dense cytoplasmic aggregates in the treated cells. These effects were more pronounced with optochin hydrochloride than with quinine hydrochloride, and they did not correlate with the relative sensitivities of different bacteria to growth inhibition by optochin or quinine.

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