Open AccessIsolation of a New Hemimethylated DNA Binding Protein Which Regulates dnaA Gene Expression
Author(s) -
Emmanuelle d’Alençon,
Aziz Taghbalout,
Claire A. Bristow,
Renée Kern,
Revital Aflalo,
Masamichi Kohiyama
Publication year - 2003
Publication title -
journal of bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.652
H-Index - 246
eISSN - 1067-8832
pISSN - 0021-9193
DOI - 10.1128/jb.185.9.2967-2971.2003
Subject(s) - biology , dnaa , gene , dna , dna binding protein , gene expression , function (biology) , microbiology and biotechnology , regulation of gene expression , genetics , transcription factor
In this report, we show that yccV, a gene of unknown function, encodes a protein having an affinity for a hemimethylated oriC DNA and that the protein negatively controls dnaA gene expression in vivo.