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Clostridium perfringens type F strains, which produceC. perfringens enterotoxin (CPE), are a major cause of gastrointestinal infections, including the second most prevalent bacterial foodborne illness and 5 to 10% cases of antibiotic-associated diarrhea. Virulence of type F strains is primarily ascribable to CPE, which is synthesized only during sporulation.

NanR Regulates Sporulation and Enterotoxin Production by Clostridium perfringens Type F Strain F4969