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The J8 peptide from the conserved region of the M protein protects against group A streptococcus infections. In this study, we demonstrate that vaccination with a J8-containing formulation induces IgG that recognizes and binds group C and G streptococci. Moreover, this formulation has the potential to provide protection against infections caused by these organisms.

In VivoEfficacy of a Chimeric Peptide Derived from the Conserved Region of the M Protein against Group C and G Streptococci