Open AccessStreptococcus pneumoniae Isolates Resistant to Telithromycin
Author(s) -
Merja Rantala,
Marjo Haanperä-Heikkinen,
Marianne Lindgren,
Helena Seppälä,
Pentti Huovinen,
Jari Jalava
Publication year - 2006
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.50.5.1855-1858.2006
Subject(s) - telithromycin , streptococcus pneumoniae , microbiology and biotechnology , erythromycin , ketolide , streptococcaceae , agar , antibacterial agent , biology , pneumococcal infections , antibiotics , virology , bacteria , genetics
The telithromycin susceptibility of 210 erythromycin-resistant pneumococci was tested with the agar diffusion method. Twenty-sixerm (B)-positive isolates showed heterogeneous resistance to telithromycin, which was manifested by the presence of colonies inside the inhibition zone. When these cells were cultured and tested, they showed stable, homogeneous, and high-level resistance to telithromycin.