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Examination of the bla(CTX-M-2) gene in plasmid pMAR-12 by sequencing and PCR analysis revealed that the bla gene and the surrounding DNA, which is closely related (99% homology) to the Kluyvera ascorbata chromosomal DNA that contains the bla(KLUA-1) gene, are located in a complex sul1-type integron, termed In35, that includes Orf513. It is possible that bla(CTX-M-2) was acquired by plasmid pMAR-12 through an uncharacterized recombinational event in which Orf513 could be involved.

bla CTX-M-2 Is Located in an Unusual Class 1 Integron (In35) Which Includes Orf513

bla _CTX-M-2 Is Located in an Unusual Class 1 Integron (In35) Which Includes Orf513