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Whole-genome sequencing was performed on 16 isolates of the carbapenemase-producing Enterobacter cloacae complex to determine the flanking regions of bla  IMI -type genes. Phylogenetic analysis of multilocus sequence typing (MLST) targets separated the isolates into 4 clusters. The bla  IMI -type genes were all found on Xer-dependent integrative mobile elements (IMEX). The IMEX elements of 5 isolates were similar to those described in Canada, while the remainder were novel. Five isolates had IMEX elements lacking a resolvase and recombinase.

antimicrobial agents and chemotherapy

Putative Integrative Mobile Elements That Exploit the Xer Recombination Machinery Carrying <i>bla</i> <sub>IMI</sub> -Type Carbapenemase Genes in Enterobacter cloacae Complex Isolates in Singapore

Putative Integrative Mobile Elements That Exploit the Xer Recombination Machinery Carrying bla IMI -Type Carbapenemase Genes in Enterobacter cloacae Complex Isolates in Singapore

Putative Integrative Mobile Elements That Exploit the Xer Recombination Machinery Carrying bla _IMI -Type Carbapenemase Genes in Enterobacter cloacae Complex Isolates in Singapore