Open AccessCharacterisation of a highly repeated DNA sequence from Mycobacterium bovis
Author(s) -
Doran T.J.,
Hodgson A.L.M.,
Davies J.K.,
Radford A.J.
Publication year - 1993
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1993.tb06377.x
Subject(s) - sequence (biology) , genetics , repeated sequence , biology , mycobacterium bovis , dna , dna sequencing , direct repeat , base pair , genomic dna , dna profiling , chromosome , computational biology , base sequence , genome , gene , mycobacterium tuberculosis , medicine , tuberculosis , pathology
Abstract We report characterisation of a novel repeat sequence from a Mycobacterium bovis genomic library. The highly repeated sequence belongs to a family consisting of a 24 base pair (bp) direct repeat (DR), that appears to be organized into clusters on the chromosome. We classify the 24‐bp DR into the group of prokaryotic DNA repeats known as the interspersed repetitive sequence elements. The 24‐bp DR will be of potential use as a DNA fingerprinting tool in epidemiological studies of M. bovis .