Open AccessExpression, purification, crystallization and preliminary X‐ray analysis of an NAD‐dependent glyceraldehyde‐3‐phosphate dehydrogenase from Helicobacter pylori
Author(s) -
Elliott Paul R.,
Mohammad Shabaz,
Melrose Helen J.,
Moody Peter C. E.
Publication year - 2008
Publication title -
acta crystallographica section f
Language(s) - English
Resource type - Journals
ISSN - 1744-3091
DOI - 10.1107/s1744309108020368
Subject(s) - glyceraldehyde 3 phosphate dehydrogenase , helicobacter pylori , nad+ kinase , dehydrogenase , crystallization , pathogen , microbiology and biotechnology , bacteria , biology , biochemistry , chemistry , enzyme , genetics , organic chemistry
Helicobacter pylori is a dangerous human pathogen that resides in the upper gastrointestinal tract. Little is known about its metabolism and with the onset of antibiotic resistance new treatments are required. In this study, the expression, purification, crystallization and preliminary X‐ray diffraction of an NAD‐dependent glyceraldehyde‐3‐phosphate dehydrogenase from H. pylori are reported.