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The morbidity and mortality rates in cystic fibrosis (CF) patients are significantly affected by infections with organisms from the Burkholderia cepacia complex (BCC). The complex currently includes nine genomic species (genomovars): Burkholderia cepacia (genomovar I), Burkholderia multivorans (genomovar II), genomovar III (divided into two recA clusters, III-A and III-B; Mahenthiralingam et al., 2000), Burkholderia stabilis (genomovar IV),Burkholderia vietnamiensis (genomovar V), genomovar VI, Burkholderia ambifaria (genomovar VII), Burkholderia anthina (genomovar VIII) and Burkholderia pyrrocinia (genomovar IX) (Vandamme, 2002). Although all genomovars have been isolated fromclinical sources, their occurrence varies significantly (Agodi et al., 2001; Speert et al., 2002), indicating the differences among the genomovars in virulence factors and in the ability of person-to-person transmissibility. Most of the virulent and epidemic strains have been identified within genomovar IIIA (Mahenthiralingam et al., 2001; Agodi et al., 2002).

Genomovar distribution of the Burkholderia cepacia complex differs significantly between Czech and Slovak patients with cystic fibrosis