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It is found by daily Experience, that Air shut up and confined in a close Place, without a Succession and fresh Supply of it, becomes unwholsome, and unfit for the Use of Life.

philosophical transactions of the royal society of london

XII. An account of Mr. Sutton's invention and method of changing the air in the hold, and other close parts of a ship; communicated to the Royal Society by Richard Mead, M. D. Physician to His Majesty, Fellow of the Royal Society, and of the Royal College of Physicians, London