Open AccessSuboptimal Nevirapine Steady-State Pharmacokinetics During Intrapartum Compared With Postpartum in HIV-1-Seropositive Ugandan Women
Author(s) -
Mohammed Lamorde,
Pauline Byakika-Kibwika,
Violet Okaba-Kayom,
John P. Flaherty,
Marta Boffito,
Rhoda Namakula,
Máirín Ryan,
Clemensia Nakabiito,
David Back,
Saye Khoo,
Concepta Merry,
Kimberly K. Scarsi
Publication year - 2010
Publication title -
journal of acquired immune deficiency syndromes
Language(s) - English
Resource type - Journals
eISSN - 1944-7884
pISSN - 1525-4135
DOI - 10.1097/qai.0b013e3181e9871b
Subject(s) - nevirapine , liter , medicine , pharmacokinetics , pregnancy , obstetrics , human immunodeficiency virus (hiv) , gestation , viral load , antiretroviral therapy , immunology , biology , genetics
Conflicting data exist regarding the effect of pregnancy on steady-state nevirapine pharmacokinetics (PK), although steady-state nevirapine concentrations during pregnancy have never been characterized in sub-Saharan Africa.