Open AccessGemfibrozil Concentrations Are Significantly Decreased in the Presence of Lopinavir-Ritonavir
Author(s) -
Kristin Busse,
Colleen Hadigan,
Cheryl Chairez,
Raul M. Alfaro,
Elizabeth Formentini,
Joseph A. Kovacs,
Scott Penzak
Publication year - 2009
Publication title -
journal of acquired immune deficiency syndromes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.162
H-Index - 157
eISSN - 1944-7884
pISSN - 1525-4135
DOI - 10.1097/qai.0b013e3181b0610e
Subject(s) - lopinavir , gemfibrozil , ritonavir , lopinavir/ritonavir , pharmacokinetics , medicine , pharmacology , area under the curve , oral administration , confidence interval , gastroenterology , cholesterol , human immunodeficiency virus (hiv) , viral load , immunology , covid-19 , antiretroviral therapy , infectious disease (medical specialty) , disease
The objective of this study was to determine the influence of a 2-week course of lopinavir-ritonavir on the pharmacokinetics of the triglyceride-lowering agent, gemfibrozil.