Open AccessThe Pharmacokinetics and Viral Activity of Tenofovir in the Male Genital Tract
Author(s) -
Manoli Vourvahis,
Hiba L. Tappouni,
Kristine B. Patterson,
Ya Chi Chen,
Naser L. Rezk,
Susan A. Fiscus,
Brian P. Kearney,
James F. Rooney,
James Hui,
Myron S. Cohen,
Angela D. M. Kashuba
Publication year - 2008
Publication title -
journal of acquired immune deficiency syndromes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.162
H-Index - 157
eISSN - 1944-7884
pISSN - 1525-4135
DOI - 10.1097/qai.0b013e3181632cc3
Subject(s) - pharmacokinetics , medicine , pharmacology , tenofovir , human immunodeficiency virus (hiv) , chemistry , virology
To measure tenofovir (TFV) concentrations in the male genital tract (GT) after single and multiple doses of tenofovir disoproxil fumarate (TDF) and evaluate the HIV-1 RNA response to monotherapy.