Open AccessImmunological control of chronic HIV-1 infection: HLA-mediated immune function and viral evolution in adolescents
Author(s) -
Anju Bansal,
Ling Yue,
Joan A. Conway,
Karina Yusim,
Jianming Tang,
John C. Kappes,
Richard A. Kaslow,
Craig M. Wilson,
Paul Goepfert
Publication year - 2007
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0b013e3282f13823
Subject(s) - elispot , immunology , cd8 , human leukocyte antigen , biology , immune system , cytotoxic t cell , hla b , virology , viral load , epitope , t cell , antigen , virus , genetics , in vitro
Differential protein targeting by HIV-specific CD8 T cells is associated with disparate plasma viral loads; however, it is unclear if the quality of these responses differs depending upon the specificity of the targeted epitopes.