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Early in the education of ophthalmologists the student is introduced to the concept of drusen. The material is presented in an efficient unquestioning manner: drusen are formed by material under the retinal pigment epithelium (RPE). This material seems to have varying composition, which may have clinically recognizable correlates.1-4 Classification systems are presented such as dividing drusen into hard or soft, or as small intermediate, or large.5-9 Each of the classification systems builds on the underlying educational principles of the location and physical characteristics of drusen.

Drusen, an Old but New Frontier