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METHODS: A collaborative protocol was developed by the PBM team, plastic surgery and anesthesia clinicians in 2016, which involved the pre-operative optimization of hemoglobin levels, the intraoperative use of tranexamic acid and CellSaverTM technology, as well as blood sparing operative techniques. Additionally, patients were preoperatively screened for altered coagulation including hypofibrinogenemia and von Willebrand’s disease. Prospective monitoring of these 17 patients in the intervention arm was collected. Retrospective data on 20 consecutive patients who underwent craniofacial surgery prior to the initiation of the program were used as a control group. The primary endpoint was the transfusion volume of blood products.

Abstract: A Craniometric Analysis of Cranial Base Differences in Unicoronal Craniosynostosis