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area burn (C57BL6 mice; n=4 per time point). Imaging of the injured limb and skin incision only contra-lateral limb (control) was performed weekly (1–9 weeks post-injury) in a longitudinal fashion. Acoustic concentration (10*log(mm-3)) was calculated for each ultrasound frame. Houndsfield units were used to calculate HO volume on microCT imaging. Histology was used to confirm the presence of HO and to correlate with imaging findings at each time point.

Abstract 55: Osseointegrated Neural Interface (ONI): Rethinking a Conventional Surgical Treatment for Amputation Neuromas in the Digital Age.