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In Israel, those with Arabic as compared to Jewish ethnicity, exhibit poorer health and motor vehicle safety behaviors. Their ethnic differences in sleep duration and quality may modulate their vulnerabilities to these behaviors. Methods 7,230 Israeli individuals (N=5,880 Jewish and N=1350 Arabic) responded to the 2017 Israeli Bureau of Statistics population-based survey of households. Variables were self-reported. Outcomes included sleepiness, sleep medications, functional impairment, drowsy driving, overall health, 1-year health change, and obesity. Predictors included categorical sleep duration (&amp;lt;=5, 6, 7, 8 [reference], or &amp;gt;=9 hours) and sleep disturbance in the past month (none [reference], mild [1/week], moderate [2-3/week], or severe [&amp;gt;3/week]). Covariates included age, sex, and financial status. Ethnicity (Jewish/Arabic) was treated as a predictor of sleep and behavioral outcomes. Results When compared to normal (8-hour) sleepers, Jewish as compared to Arabic individuals were more likely to to sleep &amp;lt;=5h (RRR=3.99, p&amp;lt;0.0005), 6h (RRR=4.65, p&amp;lt;0.0005), and 7h (RRR=3.34, p&amp;lt;0.0005), and were more likely to report severe sleep difficulties (RRR=1.49, p&amp;lt;0.0005) and sleepiness (oOR=1.52, p&amp;lt; 0.0005). Yet, they were less likely to report functional impairment (oOR=0.65, p&amp;lt;0.0005), drowsy driving (OR=0.58, p&amp;lt;0.0005), worse health (oOR=0.51, p&amp;lt;0005), worsening health (oOR=0.70, p&amp;lt;0.0005), or obesity (OR=0.64, p&amp;lt;0.0005). Significant ethnicity by sleep duration interactions (p&amp;lt;0.05) characterized sleepiness, sleep medications, functional impairment, health, and health change. Moreover, significant ethnicity by sleep disturbance interactions (p&amp;lt;0.05) characterized the same outcomes, in addition to drowsy driving. Overall, the impact of sleep duration and sleep difficulties was generally greater among Arabs for all variables. Conclusion Despite Jewish individuals endorsing relatively shorter sleep and more severe sleep difficulties, Arabs seem to be more vulnerable to the health and functional outcomes. This finding may explain some of the discrepancies in the health and safety outcomes between these ethnic groups. Support Dr. Grandner is supported by R01MD011600

0404 Jewish-Arab Disparities in Sleep Behaviors and Differential Ethnic Impact on Daytime Functioning, Driving Safety, and Health in Israel