English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

Background Antimicrobial Stewardship Programs (ASP) have the potential to improve patient outcomes, decrease bacterial resistance, increase patient safety, and decrease costs. In a private hospital without restrictions on the use of antibiotics, the improvement in antibiotic use depends mainly of prospective feedback and education. The purpose of this study was to characterize the impact of the ASP (PROA-HCB) on the appropriate selection of antibiotic prophylaxis in cesarean delivery and ceftriaxone and cefazolin utilization. Methods Retrospective analyses of six months before and six months after ASP intervention in the optimal selection of antibiotic prophylaxis (selection, dosage, duration) in cesarean delivery and consumption of ceftriaxone and cefazolin in the year of the intervention. Results Percentage of optimal selection of antibiotic prophylaxis in cesarean delivery was 0.5% (n = 553) in the pre-ASP period and 80.0% (n = 662) in the post-ASP period (76.5% absolut improvement, P < 0.001). Mean ceftriaxone utilization was 274.7 defined daily doses (DDD) per 1,000 patient days DDD for the pre-ASP period and 196.4 DDD per 1,000 patient days for the ASP period (28.5% decrease; P = 0.002). Mean cefazolin utilization was 6.4 DDD per 1,000 patient days for the pre-ASP period and 37.2 DDD per 1,000 patient days for the ASP period (581.3% increase; P = 0.002). Conclusion ASP initiatives were associated with an observed improvement on the optimal selection of antibiotic prophylaxis in cesarean delivery, reduction in ceftriaxone utilization and increase cefazolin utilization. Disclosures All authors: No reported disclosures.

open forum infectious diseases

Impact of an Antimicrobial Stewardship Program (ASP) on the Optimal Selection of Antibiotic Prophylaxis in Cesarean Delivery in a Hospital Without Restrictions on the Use of Antibiotics: First ASP in Costa Rica