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The acronym 'SAPHO' denotes the combination of urine was unremarkable. Treatment with retinoids Synostosis - Acne - Pustulosis - Hyperostosis - (TigasonA 2◊25 mg/day) was started. Osteitis; this rare syndrome is characterized by the In the fall of 1994, the patient was admitted to our occurrence of dermatoses with formation of sterile hospital for the first time. He complained of dysaes- abscesses (in the past designated as 'palmoplantar thesia and hypoaesthesia of the lower extremities. He pustulosis', 'acne pustulosa', 'psoriasis pustulosa'), was no longer able to tell whether he was wearing accompanied by sterile osteitis, resembling osteomyel- itis and articular lesions causing synostosis. So far, there have been no descriptions of the association of this syndrome with renal failure. In the following, we describe a patient, suVering from Sapho syndrome, who developed chronic renal failure second- ary to AA amyloidosis.

Renal amyloidosis and renal failure - a novel complication of the SAPHO syndrome