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The deoxyribonucleic acid-repair protein O(6)-methylguanine-deoxyribonucleic acid methyltransferase is a major determinant of resistance of cells to various alkylating drugs. Its expression profile is different in different cancer types. Here, we studied the expression and function of O(6)-methylguanine-deoxyribonucleic acid methyltransferase in clear cell renal cell carcinoma.

Impact ofO6-methylguanine-DNA methyltransferase expression on the drug resistance of clear cell renal cell carcinoma

Impact ofO⁶-methylguanine-DNA methyltransferase expression on the drug resistance of clear cell renal cell carcinoma