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The World Health Organization recommends monitoring Onchocerca volvulus Ov16 serology in children aged &lt;10 years for stopping mass ivermectin administration. Transmission models can help to identify the most informative age groups for serological monitoring and investigate the discriminatory power of serology-based elimination thresholds. Model predictions depend on assumed age-exposure patterns and transmission efficiency at low infection levels.

the journal of infectious diseases (online. university of chicago press)/the journal of infectious diseases

Structural Uncertainty in Onchocerciasis Transmission Models Influences the Estimation of Elimination Thresholds and Selection of Age Groups for Seromonitoring