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Antigenic variation in Plasmodium falciparum is mediated by the multicopy var gene family. Each parasite possesses about 60 var genes, and switching between active var loci results in antigenic variation. In the current study, the effect of mosquito and host passage on in vitro var gene transcription was investigated.

Sporozoite Route of Infection Influences In VitrovarGene Transcription ofPlasmodium falciparumParasites From Controlled Human Infections