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Evidence from mouse colitis models indicates that cytotoxic CD8+ T cells [CTL] play a key role in the initiation of gut lesions. We investigated whether changes in CD8+ CTL in blood or lamina propria [LP] of the neoterminal ileum were associated with postoperative endoscopic recurrence of Crohn's disease [CD].

journal of crohn's and colitis

Enrichment of Circulating and Mucosal Cytotoxic CD8<sup>+</sup>T Cells Is Associated with Postoperative Endoscopic Recurrence in Patients with Crohn’s Disease

Enrichment of Circulating and Mucosal Cytotoxic CD8+T Cells Is Associated with Postoperative Endoscopic Recurrence in Patients with Crohn’s Disease

Enrichment of Circulating and Mucosal Cytotoxic CD8⁺T Cells Is Associated with Postoperative Endoscopic Recurrence in Patients with Crohn’s Disease