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Background/Introduction: B-lymphocytes have critical roles in the inflammatory process that drives atherosclerosis. In animal models, conventional B2 B cells promote atherosclerosis, whilst innate B1a B cells are protective. B cells with regulatory function (Bregs) have been identified in animals and humans and have been implicated in the pathogenesis of autoimmunity. Whether Bregs have a role in human atherosclerosis is currently unknown.

cardiovascular research

Moderated Poster session - Vascular26Identification of CMTM3 as a new pro-angiogenic factor essential for vessel stabilization27Regulation of pulmonary vascular PW1+ progenitor cells recruitment during early chronic hypoxia-induced vessel neomuscularization28Impaired interleukin-10 production in response to CpG and depletion of the regulatory CD19+CD24hiCD38hi B cell compartment in patients with coronary atherosclerosis29Inflammatory effects of serum amyloid A via TLR2 and TLR4 in vascular …