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Does “time of flight” evoke thoughts of your next business trip? Are you a director of a laboratory considering purchasing a mass spectrometer who needs to gain a working knowledge of its capabilities in your laboratory? Is it time to update and improve your testing methods? A Global View of LC/MS introduces you to the rapidly expanding universe of mass spectrometry in an easy-to-read, unique “decision-tree” structured guide. This book is not only valuable as an introduction to mass spectrometry but is equally useful as a guide to structured problem solving in the laboratory. As the authors state, “solving problems is what it [the real world] is all about”.Understanding the principles of mass spectrometry is a formidable task; understanding how to use this instrumentation effectively is even more challenging. R. Willoughby, E. Sheehan, and S. Mitrovich have written a guidebook for beginning this process. They have organized the text into five parts using a variety of flow charts, checklists, decision trees, and worksheets. The thought processes begin with the problem definition. This flows into decisions …

clinical chemistry

A Global View of LC/MS. How To Solve Your Most Challenging Analytical Problems. Ross Willoughby, Edward Sheehan, and Samuel Mitrovich. Pittsburgh, PA: Global View Publishing, 1998, 554 pp. Paperback. $49.95. ISBN 0-9660813-0-7.