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Productivity of wheat is affected by drought stress; however, the correlation between drought stress and metabolism is still not clear. The aim of this study was to investigate physiological adaptive mechanisms and reveal physiological processes related to drought tolerance. The results indicated that the wheat metabolome is dominated by sugars, organic acids and amino acids; the wheat metabolome plays important roles in enhancing the drought tolerance of shoots. Drought caused system alterations in widespread metabolic networks involving transamination, tricarboxylic acid cycle, glycolysis, glutamate-mediated proline biosynthesis, shikimate-mediated secondary metabolisms and GABA metabolisms.

Metabolic responses to drought stress in the tissues of drought-tolerant and drought-sensitive wheat genotype seedlings