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Animal researches reported that the dysfunction of profilin1 (PFN1) was involved in the physiological arterial stiffness and vascular remodeling linking to the etiology of hypertension (HT). This study mainly aims at evaluating the association of PFN1 and HT in a Han Chinese population.

Association Study of Common Variants in PFN1 With Hypertension in a Han Chinese Population: A Case–Control Study and A Follow-up Study